There is another thread running with "what is your go to cigar"; I didn't post because I don't have a specific stick that qualifies.
My choice changes daily, depending on my mood, time of day, beverage choice and other factors. I do have a number of favorites on hand, just to allow me to make a choice at that time.
So, in answer to your question, I change profiles all the time. I don't think I have ever smoked the same cigar twice in a row. There are just too many cigars out there, most of which I have yet to try!