How tight are you wearing the watch?  This sounds to me either like a reaction to a metal used in the band/case back or your skin reacting to extended pressure and a lack of breathability under the strap.  If it's either of those simple hydro-cortisone (or similar) steroid creme and leaving the watch off for a few days should clear it right up.  If it's the breathablity issue than just take your watch off at night and that should prevent it from recurring.  If not get a referral to a dermatologist and consult an expert 
