The idea of the .22 is great. You can buy 500 rounds for about 20 bucks and shoot all day. The Buckmark eats just about any type of ammo you put in it. I love my .22's.

That said, pretty hard to beat the solid thump of a 1911 but paying for the pistol and the ammo is another story entirely.
I have a Sig 226 and it's a fine pistol but if I were to buy another 9mm I'd go with the Beretta 92FS just as a matter of personal preference. Feels better in my hand and I am more accurate w/ those things for some reason.