The 80th's, 40th,s 45th's, 46's, '26's and 64's all have top grade A tobaccos. The difference is the age of the tobaccos. Construction should be second to none on all of these.
Nicotine perception is all about physicality for everyone. Some days it hit's you harder than others. The difference, who knows?
I have found when you are not expecting alot of nicotine it can sneak up on you quicker than you realize.